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Alli is a medication used to help weight loss. It contains the active ingredient orlistat, and works by blocking some of the fat you eat, preventing it from being absorbed by your body.
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What is Alli?

Alli contains the active ingredient Orlistat. It is the first over-the-counter drug designed to treat obesity. It blocks some of the fat you eat, preventing it from being absorbed by your body.


When taken alongside a reduced-calorie diet, Alli can help you lose up to 50% more weight than dieting alone.

How does Alli work?

Fat Absorption without Alli

Fat is too large to be absorbed by the body

It is broken down by enzymes into smaller parts that the body can absorb

Once broken down, the smaller molecules are easily absorbed by the body


Fat Absorption with Alli

When you take Alli with a well-balanced diet it blocks some of the enzymes from breaking down the fat

This reduces the amount of fat that is absorbed by the body


Larger fat molecules cannot be absorbed by the body and are thus excreted

How do you take Alli?

Always take this medication as prescribed to you by your doctor or pharmacist.


Take one Alli weight loss tablets can be taken immediately before, during, or up to one hour after a meal. Take ONE capsules three times daily, ideally before each meal. Do not exceed more than directed.

How effective is Alli?

Alli is an effective way of losing weight if taken alongside a reduced-calorie diet. In addition to taking Alli, you should be on a calorie-restricted diet and should be exercising. Talk to your doctor or weight loss specialist for more information on diet and exercise.

What are the main side effects of Alli?

Like all medicines, Alli can cause side effects. However, not everybody experiences them. Side effects are usually mild to moderate and only last a short duration.


The most common side effects of Alli are:

  • Headache
  • Abdominal pain or discomfort
  • Low blood sugar levels (experienced by some people with type 2 diabetes)


For less frequent side effects, please see the patient information leaflet.

More Information
Dosage 60 mg
Dosage Instructions Please see medicine label for the dosage instructions.