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Celebrex

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EC000005
Celebrex is a non-steroidal anti-inflammatory drug, used for pain relief. It works by stopping the effects of hormones that cause pain and inflammation.
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Celebrex

What is Celebrex?

Celebrex is part of a group of medications called non-steroidal anti-inflammatory drugs. It is used for the relief of pain, inflammation, fever and swelling caused by certain conditions that affect the joints, such as rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, as well as other types of acute pain such as menstrual pain.

Celebrex is available on prescription, however it is possible for us to prescribe it to you online after an assessment to see whether it is suitable for you.

Celebrex is a brand name - the active ingredient is celecoxib. Generic versions are also available.

For more information on Celebrex, you should read the patient information leaflet.

How it works

Celebrex is a COX inhibitor, meaning it stops the production of a natural substance in the body called COX. This substance is responsible for pain and inflammation, so by inhibiting it, it prevents you feeling pain. This is in much the same way as other NSAIDs - reducing the effect of hormones that cause you to feel pain.

Celebrex generally begins to work within one hour, but it could be several days before you feel its full effects. Celebrex is usually prescribed as 100mg or 200mg capsules. Celebrex may be taken long term to help manage the symptoms of chronic pain conditions.

Before you take it

You should not take Celebrex if you have an allergy to any of the ingredients within. This includes the active ingredient, Celecoxib. It may also contain gelatin or lactose, so if you have an allergy to these ingredients, speak with your doctor before using Celebrex.

You should not take Celebrex before or just after having coronary artery surgery (heart bypass.)

Celebrex has been known to cause harm to unborn children if taken within the last trimester of pregnancy. If you are pregnant or trying to become pregnant, you should speak with your doctor before taking Celebrex. You should also discuss methods of contraception with your doctor if you do not want to become pregnant while taking Celebrex.

You should not breastfeed while taking Celebrex - this is because it passes into breast milk.

Celebrex, like other NSAIDs, can increase your risk of having a heart attack or stroke. If you have heart disease, or a history of heart, liver or kidney problems, you must speak with your doctor to discuss alternative treatment for your condition.

Celebrex has been associated with an increased risk of stomach ulcers and bleeding in the stomach or intestines in some patients, especially the elderly. This can occur without warning. If you have a history of internal bleeding, you should speak with your doctor before taking Celebrex.

Celebrex, when taken to treat arthritis, can cause your blood glucose to increase. You should take particular care to monitor your blood glucose if you’re taking Celebrex and you have diabetes.

Celebrex may interact with certain medications. You should speak with your doctor or pharmacist if you are taking any of the following, as they may cause drug interactions with Celebrex:

  • Fluconazole and rifampicin, used to treat bacterial infections
  • Other NSAIDs, such as ibuprofen or naproxen
  • Warfarin, aspirin or any other medicines used to thin the blood
  • Any medicines used to treat sleep disorders (such as Zopiclone or Zolpidem)
  • Any medicines used to treat depression (such as Citalopram or Fluoxetine)
  • Methotrexate, used to treat arthritis or psoriasis
  • Barbiturates, used to treat epilepsy
  • Neuroleptics used to treat mental disorders

This list is not exhaustive, and for a full list of drug interactions and warnings before taking Celebrex, you should ask your doctor or refer to the patient information leaflet.

Dosage Instructions

You should take Celebrex exactly as your doctor has prescribed. Do not exceed your prescribed dose, as this can cause adverse effects. You should take the lowest effective dose that treats your system. Do not take Celebrex for longer than prescribed.

The usual recommended dose for adults is 200 mg daily, taken as a 200mg dose once daily or a 100 mg twice daily. This may be increased at your doctor’s discretion if needed.

You should swallow your Celebrex capsules whole. Do not crush, suck or chew them.

You don’t need to take Celebrex at a specific time of the day, as long as you take your capsules at the same time every day. Swallow them with plenty of water. Celebrex can be taken with or without food.

The maximum daily dose of Celebrex is 400 mg. You should never exceed this.

If you do not start to feel better within two weeks of starting treatment, you should first consult your doctor.

You should store Celebrex at room temperature, out of the reach of children and pets.

Common Side Effects of Celebrex

Celebrex has the potential to cause serious allergic reactions in some people. This is an emergency, and if you believe you are having an allergic reaction of any kind you must immediately seek medical advice. Related side effects can include:

  • Trouble breathing or speaking
  • Chest pains
  • Wheezing
  • Hives
  • Skin rash, including redness, peeling, itching, blistering
  • Swelling of the face, including the lips, mouth, tongue, nose or throat

Celebrex may also cause serious side effects in some patients. You should consult your doctor right away if you are suffering from any of the following:

  • Heart Attack
  • Shortness of breath
  • Stroke
  • Heart failure
  • Increased likelihood of bleeding
  • Hallucinations
  • Hair Loss
  • Black, tarry stools
  • Vomit that contains blood or looks like coffee grounds

Celebrex can also cause less serious, more common side effects. These are usually mild to moderate in nature and should go away on their own as your body becomes used to the medicine. However, if they do not go away, or they concern you, speak with your doctor. They can include:

  • Headache
  • Urinary Infections
  • Muscle stiffness
  • Difficulty swallowing
  • Painful joints
  • Worsening of existing allergies
  • Blocked or painful sinuses
  • Nausea
  • Dizziness or drowsiness
  • Weight gain

This list is not exhaustive. For a full list of potential side effects of Celebrex, consult the patient information leaflet or contact your doctor.


Frequently Asked Questions (FAQs)


Is Celebrex safe for children?

No. Celebrex is unsuitable for children to take under any circumstances. We do not prescribe any medication to anyone under 18 years of age.

I’m pregnant. Can I take Celebrex?

You should not take Celebrex if you are pregnant. This is because it has the potential to cause harm to an unborn baby. If you are pregnant or become pregnant while taking Celebrex, inform your doctor to discuss an alternative treatment.

What happens if I miss a dose?

Sometimes patients who are on Celebrex are not on a dosing schedule. If this is the case, you should only use Celebrex when you need it. If you are on a dosing schedule and you miss a dose, you should take it as soon as you remember, unless it is nearly time for your next dose. If this is the case, skip the missed dose and continue with your next dose as normal. Never double up to make up for a missed dose.

What happens if I take too much?

An overdose of Celebrex can cause serious health problems. Common side effects of an overdose include tiredness, weakness, internal bleeding, high blood pressure and abdominal pain. In higher quantities it can induce a coma. If you believe you have overdosed on Celebrex, you should immediately go to your local hospital or A&E department for emergency medical treatment.

More Information
Dosage No
Dosage Instructions Please see medicine label for the dosage instructions.