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Colofac (Mebeverine 135mg)

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Colofac Mebeverine is a medication used to treat symptoms of irritable bowel syndrome, such as abdominal cramps, diarrhoea and flatulence. This medication works by relaxing the muscles of the gut, relieving bowel spasms and abdominal pain.
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What are Colofac (Mebeverine 135mg) tablets?

Colofac (Mebeverine 135mg) tablets are an antispasmodic medication used in the treatment of IBS symptoms including abdominal pain and cramps, diarrhoea and flatulence. Mebeverine tablets are the generic version of the medication, whereas Colofac is the branded version. Both contain the same active ingredient, mebeverine hydrochloride.  

These tablets contain lactose, so if you have an intolerance you should seek medical advice before taking these tablets.

How do Colofac (Mebeverine 135mg) tablets work?

As food passes through the digestive system of someone with IBS, the intestine can go into spasm. Colofac (Mebeverine 135mg) tablets contain an active ingredient called mebeverine hydrochloride, which works to relax the muscles of the gut. This helps to relieve bowel spasms and abdominal pain.

How do you take Colofac (Mebeverine 135mg) tablets?

You should always take Colofac (Mebeverine 135mg) tablets as directed by your doctor or pharmacist. The dose for adults is one tablet three times a day. This dose may be gradually lowered if symptoms improve. Colofac (Mebeverine 135mg) is not recommended for anyone under the age of 18.

It is best to take the tablet around 20 minutes before eating a meal, since symptoms are often at their worst after meals. Take the tablet with at least 100ml of water, and do not chew it.

How effective are Colofac (Mebeverine 135mg) tablets?

Colofac (Mebeverine 135mg) tablets are effective at relieving abdominal pain and spasms.

As well as taking Colofac (Mebeverine 135mg), there are other ways of managing IBS symptoms. Examples include:

  • Eating regular meals and taking your time when eating.
  • Drinking plenty of water.  
  • Taking time to relax when possible.

The IBS Network also recommends self-help methods such as deep breathing, taking a hot bath, or holding a hot water bottle to your abdomen. Read more suggestions on the IBS Network article on managing abdominal pain

What are the side effects of Colofac (Mebeverine 135mg) tablets?

Like all medicines, Colofac (Mebeverine 135mg) tablets can cause side effects, although not everyone will experience them. The most common side effects are:

  • Allergic reactions including skin reactions, reddened skin, swelling, hives, itching and skin rashes.

For more information, please see the patient information leaflets: Colofac 135mg and Mebeverine 135mg. If you experience any side effects, you can report them through the Yellow Card Scheme set up by the MHRA. 

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Dosage Instructions Take ONE tablet THREE times a day.