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Sirdupla Inhaler

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EC33687
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Sirdupla Inhaler

What is Sirdupla Inhaler?

The Sirdupla 25/125 25/250 metered dose pressurised inhalation powder (also referred to as Sirdupla throughout this information), is used to treat the symptoms of mild to severe asthma. Sirdupla is used every day to help prevent asthma attacks.

Sirdupla contains two active substances, salmeterol and fluticasone propionate.

Budesonide belongs to a group of medicines called corticosteroids. Corticosteroids work by preventing and reducing swelling and inflammation in the lungs. Formoterol fumarate dihydrate is a steroid and long-acting bronchodilator which works to relax the muscles in the airways. It is used to prevent bronchospasm in people with asthma or chronic obstructive pulmonary disease (COPD).

Salmeterol is a long-acting bronchodilator that helps for up to 12 hours for the relief of closed airways. This enhances airway function and aids in easier breathing.

Fluticasone propionate is a glucocorticosteroid. This active ingredient is a type of steroid hormone that has anti-inflammatory properties that reduce inflammation of the body.

For further information on Sirdupla, please see the Patient Information Leaflet here.

How it works

The Sirdupla Inhaler is used for chronic obstructive pulmonary disease and asthma control. This treatment is also known as a ‘preventer’. This is because it helps to prevent asthma symptoms and should not be used during an asthma attack.

The Sirdupla inhaler is used to treat asthma symptoms by preventing swelling and inflammation deep within the lungs and airways. It is used to aid symptoms of asthma to make it easier to breathe.

Before you take it

Most healthy adults and adolescents aged over 17 are safe using the Sirdupla Inhaler. It is not recommended for use by children under 12 years of age without direct medical advice or supervision from a healthcare professional. We do not prescribe any medications to people under 18 years old.

It is important for your own health and safety that if you already suffer symptoms of an allergic reaction related to beclometasone dipropionate, previously inhaled corticosteroids, formoterol fumarate dihydrate or any other ingredient in this drug, you should talk to your doctor or pharmacist before taking the Sirdupla inhaler.

The Sirdupla Inhaler contains small amounts of milk protein and the lactose sugar. If you have an intolerance to milk or dairy, it is advised to approach your doctor before using the Sirdupla Inhaler.

This inhaler will not give immediate relief to wheezing or breathlessness during a sudden asthma attack. Instead, an inhaler prescribed for asthma known as ‘Reliever’ or ‘rescue’ inhalers are quick-acting and should be used to relieve an asthma attack. ‘Reliever’ and ‘rescue’ inhalers are not the same. Carry a ‘reliever’ asthma inhaler with you at all times as it helps you to breathe during an asthma attack.

The Sirdupla Inhaler is unsuitable for some patients. You should contact your doctor or healthcare professional if any of the following apply:

  • You are suffering from tuberculosis or have suffered it in the past
  • Are allergic to similar inhalers
  • Your asthma is appearing to be getting worse
  • Your ‘reliever’ inhaler is becoming less effective
  • You are taking Disulfiram
  • You are taking Metronidazole
  • You have problems with your thyroid or adrenal glands
  • Are intolerant to medicine that contains lactose
  • You have high blood pressure have ever had a heart problem including an uneven heart beat, narrowing of the arteries or heart failure

Dosage Instructions

The prescribed Sirdupla Inhaler dosage for adults and adolescents over 18 years of age varies depending on the use of other medication. Read the information carefully before using this medicine to ensure you use the correct dosage and inhaler technique.

Sirdupla must be used every day or until your doctor advises you to stop.

Sirdupla 25/125 microgram per metered dose for adults over the age of 18, two puffs twice a day.

If symptoms do not improve, do not take extra doses from the Sirdupla inhaler in one go or self-administer a higher dose that is not controlled by your doctor.

Common Side Effects of Sirdupla Inhaler

Possible but less serious side effects of the Sirdupla Inhaler are:

  • Hoarseness and throat irritation
  • Difficulty swallowing
  • Change in taste
  • Feeling sick or nauseous
  • Headache
  • A yeast infection in the mouth (This is less likely if you rinse your mouth out with water after using the inhaler)

In case of serious side effects, stop taking treatment and call a doctor for symptoms such as:

  • Dizziness
  • Being sick or vomiting
  • Blurred vision or other visionary obscurities
  • Slow or slurred speech
  • Abdominal pain
  • Weakness

In addition, it has been reported that taking high doses over prolonged periods of time, it is likely for this medicine to have some possible side effects. There is a risk of side effects such as clouding of the lens of the eye, bone thinning and reduced vision while using Sirdupla.

It is possible that you are allergic to some of the ingredients in this medication. Please tell your doctor at once if you show signs of an allergic reaction such as:

  • Skin rash
  • Breathing problems
  • Inflammation of the legs, arms, face, lips, throat, or tongue
  • Increased heart rate
  • Confusion or anxiety

If you are experiencing an allergic reaction, stop using the Sirdupla Inhaler and tell your doctor right away to ensure you will be with appropriate supervision.



Frequently Asked Questions (FAQs)


Is Sirdupla Inhaler suitable for childen?

The Sirdupla Inhaler is not recommended for children 17 years of age or younger. Use in children should always be advised by a healthcare professional.

Do I need a prescription?

Yes. Corticosteroid inhalers are only available on prescription.

I'm pregnant. Can I take Sirdupla Inhaler?

Consult your doctor first before using this medication during pregnancy, breastfeeding or if you suspect you may be pregnant.

What happens if I miss a dose?

If you forget to take your prescribed dose at the right time, take your recommended amount of medicine as soon as you remember. If it is close to your next dose, skip the missed dose and your take treatment when it is time to use your inhaler again to continue with your regular treatment. Never double dose to make up for a missed or forgotten dose.

What happens if I take too much?

It is important to never increase or decrease the number of inhalations unless your doctor tells you to. Always use this medication in accordance with your prescription. If you have accidentally inhaled more puffs than intended or than what is recommended, please call your doctor.

If you do not seem to be getting better or become more wheezy or short of breath and you need to take more puffs from your ‘reliever’ than usual, you should check with your doctor to ensure you are being given the correct dosage and treatment. They may increase your dosage or alter medication.

More Information
Dosage No
Dosage Instructions Inhale TWO puffs TWICE a day