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Malarone is a medication used to treat and prevent malaria. Malaria is a tropical disease spread through bites from infected mosquitoes. It works by killing the parasite that causes malaria after it has been released into the bloodstream.
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What is Malarone?

Malarone is used to prevent and treat malaria. It is taken two days prior to leaving for your trip. You must continue taking it while in the malaria risk zone and for seven days upon leaving the malarious area.


It is important to note that it is still possible to get malaria even after taking the necessary precautions/ Some types of malaria take a long time to cause symptoms, so the illness may not start until several days, weeks, or even months after returning from abroad. See a doctor immediately if you experience the following symptoms after returning home:

  • High temperature
  • Headache
  • Shivering
  • Tiredness

How does Malarone work?

Malarone belongs to a group of medicines called antimalarials. It contains two active ingredients, atovaquone and proguanil hydrochloride.


Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite into the bloodstream. Malarone prevents malaria by killing this parasite. For people who are already infected with malaria, Malarone kills these parasites.

How do you take Malarone?

Always take this medication exactly as your doctor or pharmacist has prescribed it to you.


Take one tablet daily starting two days prior to leaving for your trip. Continue taking Malarone for the entire duration of your trip to the malaria risk zone. You must continue to take Malarone for seven days upon leaving the malaria risk zone.


It is very important to complete the entire course of this medication. Failing to do so could leave you vulnerable to the malaria virus.

How effective is Malarone?

Malarone is an effective antimalarial treatment. For increased results, take Malarone at the same time each day, with food or a milky drink where possible. This will increase the amount of Malarone your body can absorb, ultimately making your treatment more effective.


In addition to taking an antimalarial medication, there are special precautions you should take to avoid being bitten by infected mosquitos. These include:

  • Use insect repellent on exposed areas of the skin
  • Wear light coloured clothing that covers most of the body
  • Sleep in a screened room or under a mosquito net
  • Close windows and doors at sunset
  • Consider using an insecticide (mats, sprays, plug-ins)

What are the side effects of Malarone?

Like all medicines, Malarone can cause side effects. Not everybody will experience side effects and they are usually mild to moderate in nature and will only last a short period of time.


The most common side effects of Malarone are:

  • Headache
  • Nausea and vomiting
  • Stomach discomfort


For less frequent side effects, please see the patient information leaflet.

More Information
Dosage 250mg/100mg
Dosage Instructions Take ONE daily with food, 1 to 2 days before, during and for 7 days after leaving malarious area.